Description

Ethyl 2-Bromo-6-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine and bromine substituents for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions and asymmetric catalysis.
• Material Science Research: Employed in the synthesis of fluorinated liquid crystals, polymers, and organic electronic materials for their unique electronic and physical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	Ethyl 2-Bromo-6-Fluorobenzoate
CAS No.	1214362-62-5
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Bromo-6-fluorobenzoic acid ethyl ester; Ethyl 2-bromo-6-fluorobenzoate; Benzoic acid, 2-bromo-6-fluoro-, ethyl ester; 6-Fluoro-2-bromobenzoic acid ethyl ester; Ethyl 6-fluoro-2-bromobenzoate; 2-Bromo-6-fluorobenzoic acid, ethyl ester; Ethyl α-bromo-6-fluorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Bromo-6-Fluorobenzoate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and development. Our standard quality commitment includes HPLC purity ≥98% (with higher grades available), identity confirmation by FT-IR and NMR, and control of key impurities. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom specifications can be developed to support your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.