Description

Ethyl 2-Fluoro-3-Methoxybenzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine and methoxy substituents, which are crucial for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Organic Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Flavor & Fragrance Chemistry: Acts as a potential intermediate for creating complex aromatic esters with unique sensory profiles.
• Academic & Contract Research: Essential for methodological studies in cross-coupling reactions and fluorination chemistry within university and CRO laboratories.

Basic Information

Product Name	Ethyl 2-Fluoro-3-Methoxybenzoate
CAS No.	1214346-45-8
Molecular Formula	C10H11FO3
Molecular Weight	198.19 g/mol
Synonyms	2-Fluoro-3-methoxybenzoic acid ethyl ester; Ethyl 2-fluoro-3-methoxybenzoate; Benzoic acid, 2-fluoro-3-methoxy-, ethyl ester; 3-Methoxy-2-fluorobenzoic acid ethyl ester; Ethyl 3-methoxy-2-fluorobenzoate; 2-Fluoro-m-anisic acid ethyl ester; Ethyl o-fluoro-m-methoxybenzoate; FEMA 4606 (related flavor compound)
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-3-Methoxybenzoate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing parameters such as assay (by HPLC), impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.