Description

3-Chloro-5-Fluoro-2-Hydroxypyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized organic materials and electronic chemicals.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific halogenated heterocyclic frameworks.

Basic Information

Product Name	3-Chloro-5-Fluoro-2-Hydroxypyridine
CAS No.	1214345-43-3
Molecular Formula	C5H3ClFNO
Molecular Weight	147.54 g/mol
Synonyms	2-Hydroxy-3-chloro-5-fluoropyridine; 3-Chloro-5-fluoro-2(1H)-pyridinone; 3-Chloro-5-fluoropyridin-2-ol; 5-Fluoro-3-chloro-2-hydroxypyridine; 3-Chloro-5-fluoro-2-pyridinol
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-2-Hydroxypyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.