Description

5-Chloro-3-(trifluoromethyl)-2(1H)-pyridinone is a high-value, multi-functional heterocyclic building block characterized by its unique combination of chlorine and trifluoromethyl substituents. This compound is of significant commercial interest due to its role as a key synthetic intermediate in the development of advanced active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the CF3 group.
• Material Science Research: Used in the development of specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	5-Chloro-3-(trifluoromethyl)-2(1H)-pyridinone
CAS No.	1214342-70-7
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	5-Chloro-3-(trifluoromethyl)-1H-pyridin-2-one; 5-Chloro-3-(trifluoromethyl)pyridin-2(1H)-one; 2(1H)-Pyridinone, 5-chloro-3-(trifluoromethyl)-; 5-Chloro-3-trifluoromethyl-2(1H)-pyridone; 5-Chloro-3-trifluoromethyl-1H-pyridin-2-one
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 5-Chloro-3-(trifluoromethyl)-2(1H)-pyridinone is analyzed to ensure it meets the high-purity standards required for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. The compound should be kept under an inert atmosphere for prolonged storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.