Description

Ethyl 3-(Trifluoromethyl)-4-Pyridinecarboxylate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its structure, featuring both a carboxylate ester and a trifluoromethyl group, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at research and development teams within the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and oncology research.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Research: Precursor for fluorinated liquid crystals, organic semiconductors, and other functional materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for custom synthesis projects.

Basic Information

Product Name	Ethyl 3-(Trifluoromethyl)-4-Pyridinecarboxylate
CAS No.	1214337-41-3
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	4-Pyridinecarboxylic acid, 3-(trifluoromethyl)-, ethyl ester; Ethyl 3-(trifluoromethyl)isonicotinate; Ethyl 3-trifluoromethylpyridine-4-carboxylate; 3-(Trifluoromethyl)isonicotinic acid ethyl ester; 4-Carbethoxy-3-(trifluoromethyl)pyridine; Isonicotinic acid, 3-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-(Trifluoromethyl)-4-Pyridinecarboxylate is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.