Description

6-Bromo-5-Fluoro-Nicotinic Acid Methyl Ester is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for metal-catalyzed reactions and organocatalysts.
• Life Science Research: Employed in biochemical and pharmacological studies as a tool compound for probing biological pathways.

Basic Information

Product Name	6-Bromo-5-Fluoro-Nicotinic Acid Methyl Ester
CAS No.	1214336-88-5
Molecular Formula	C8H6BrFNO2
Molecular Weight	262.04 g/mol
Synonyms	Methyl 6-Bromo-5-fluoronicotinate; 5-Fluoro-6-bromonicotinic Acid Methyl Ester; 6-Bromo-5-fluoro-3-pyridinecarboxylic Acid Methyl Ester; 6-Bromo-5-fluoropyridine-3-carboxylic Acid Methyl Ester; 3-Carbomethoxy-6-bromo-5-fluoropyridine; Methyl 6-Bromo-5-fluoro-3-pyridinecarboxylate; 1214336-88-5; 6-Bromo-5-fluoro-3-pyridinecarboxylic acid, methyl ester
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Fluoro-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and commercial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.