Description

Methyl 3,6-Difluoropicolinate is a high-purity fluorinated picolinate ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of fluorine atoms, which are essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the difluoro motif enhances lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and advanced polymers with tailored properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic chemistry for catalyst development.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 3,6-Difluoropicolinate
CAS No.	1214336-10-3
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	3,6-Difluoropyridine-2-carboxylic acid methyl ester; Methyl 3,6-difluoropyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3,6-difluoro-, methyl ester; 3,6-Difluoropicolinic acid methyl ester; Methyl 3,6-difluoro-2-pyridinecarboxylate; 1214336-10-3; Difluoropicolinate ester
EINECS	Contact for details

Quality Control

Our Methyl 3,6-Difluoropicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound may be moisture-sensitive; ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.