Description

Ethyl 6-Bromo-2-Chloronicotinate is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. This compound is valued for its unique halogenated pyridine structure, which enables precise molecular modifications in complex chemical pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its halogenated structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in cross-coupling reactions and other metal-mediated transformations.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) requiring specific halogenated nicotinate derivatives.

Basic Information

Product Name	Ethyl 6-Bromo-2-Chloronicotinate
CAS No.	1214335-22-4
Molecular Formula	C8H7BrClNO2
Molecular Weight	264.50 g/mol
Synonyms	Ethyl 6-bromo-2-chloropyridine-3-carboxylate; 2-Chloro-6-bromonicotinic Acid Ethyl Ester; 6-Bromo-2-chloro-3-pyridinecarboxylic Acid Ethyl Ester; 3-Pyridinecarboxylic acid, 6-bromo-2-chloro-, ethyl ester; Ethyl 2-chloro-6-bromonicotinate; 1214335-22-4; Ethyl 6-bromo-2-chloro-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-Bromo-2-Chloronicotinate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets a typical purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and relevant physical data to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.