Description

Methyl 2-Bromo-6-Chloronicotinate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive halogen sites, which enable precise molecular construction in complex chemical pathways. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly for candidates targeting neurological and oncological disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating specialized ligands, polymers, and functional materials with tailored electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of bromo and chloro substituents.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological evaluation.

Basic Information

Product Name	Methyl 2-Bromo-6-Chloronicotinate
CAS No.	1214335-05-3
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	Methyl 2-bromo-6-chloropyridine-3-carboxylate; 2-Bromo-6-chloronicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 2-bromo-6-chloro-, methyl ester; Methyl 2-bromo-6-chloro-3-pyridinecarboxylate; 2-Bromo-6-chloro-3-methoxycarbonylpyridine; 6-Chloro-2-bromonicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-6-Chloronicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.