Description

3-Iodo-5-(Trifluoromethyl)Pyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining an iodine substituent with a trifluoromethyl group on the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is particularly valuable for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require precise functionalization for drug discovery and specialty chemical development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and organometallic catalysts.
• Functional Material Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers where the iodine atom allows for further functionalization via metal-halogen exchange.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and labeling strategies in probe and tracer molecule development.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Iodo-5-(Trifluoromethyl)Pyridine
CAS No.	1214333-22-8
Molecular Formula	C6H3F3IN
Molecular Weight	272.99 g/mol
Synonyms	5-(Trifluoromethyl)-3-iodopyridine; 3-Iodo-5-(trifluoromethyl)pyridine; 3-Iodo-5-trifluoromethylpyridine; Pyridine, 3-iodo-5-(trifluoromethyl)-; 1214333-22-8
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-(Trifluoromethyl)Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards of research and industrial synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management systems to support our customers' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.