Description

Ethyl 5-Bromo-2-Fluoroisonicotinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacologically active compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the fluorinated pyridine core.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and liquid crystals.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 5-bromo-2-fluoropyridine moiety into more complex molecular architectures via cross-coupling reactions.
• Life Science Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.

Basic Information

Product Name	Ethyl 5-Bromo-2-Fluoroisonicotinate
CAS No.	1214332-81-6
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	5-Bromo-2-fluoroisonicotinic acid ethyl ester; Ethyl 5-bromo-2-fluoropyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 5-bromo-2-fluoro-, ethyl ester; 2-Fluoro-5-bromoisonicotinic acid ethyl ester; 5-Bromo-2-fluoro-4-pyridinecarboxylic acid ethyl ester; 1214332-81-6; Ethyl 5-bromo-2-fluoropyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-2-Fluoroisonicotinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.