Description

Ethyl 5-Nitro-2-(Trifluoromethyl)Benzoate is a high-purity, synthetically valuable trifluoromethylated aromatic ester. This compound is a critical advanced intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for use in medicinal chemistry, process development, and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing drug candidates, particularly in therapeutic areas targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the nitro and trifluoromethyl groups.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Synthesis: Employed in organic synthesis for further functionalization, including reduction of the nitro group or hydrolysis of the ester, to create a diverse library of derivatives.

Basic Information

Product Name	Ethyl 5-Nitro-2-(Trifluoromethyl)Benzoate
CAS No.	1214332-64-5
Molecular Formula	C10H8F3NO4
Molecular Weight	263.17 g/mol
Synonyms	Ethyl 5-nitro-2-(trifluoromethyl)benzoate; 5-Nitro-2-(trifluoromethyl)benzoic Acid Ethyl Ester; Benzoic acid, 5-nitro-2-(trifluoromethyl)-, ethyl ester; Ethyl 5-nitro-α,α,α-trifluoro-o-toluate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Nitro-2-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.