Description

Ethyl 3-Chloro-6-(Trifluoromethyl)Pyridine-2-Carboxylate is a high-value pyridine derivative and a crucial synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential building block for creating complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl groups.
• Material Science Research: Used in the development of specialty chemicals, liquid crystals, and advanced polymers requiring specific electronic or steric properties.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and enzyme inhibitors to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 3-Chloro-6-(Trifluoromethyl)Pyridine-2-Carboxylate
CAS No.	1214332-53-2
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.60 g/mol
Synonyms	Ethyl 3-chloro-6-(trifluoromethyl)pyridine-2-carboxylate; 3-Chloro-6-(trifluoromethyl)picolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 3-chloro-6-(trifluoromethyl)-, ethyl ester; Ethyl 3-chloro-6-(trifluoromethyl)picolinate; 1214332-53-2; Ethyl 3-chloro-6-trifluoromethylpicolinate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Chloro-6-(Trifluoromethyl)Pyridine-2-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.