Description

Methyl 6-Bromo-3-Fluoropyridine-2-Carboxylate CAS NO 1214332-47-4 is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active molecule research.
• Agrochemical Development: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluoropyridine scaffold.
• Ligand & Catalyst Synthesis: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials and liquid crystals due to its halogenated pyridine core.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	Methyl 6-Bromo-3-Fluoropyridine-2-Carboxylate
CAS No.	1214332-47-4
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	Methyl 6-bromo-3-fluoropicolinate; 2-Pyridinecarboxylic acid, 6-bromo-3-fluoro-, methyl ester; 6-Bromo-3-fluoropyridine-2-carboxylic acid methyl ester; Methyl 6-bromo-3-fluoropyridine-2-carboxylate; 1214332-47-4; Methyl 2-bromo-5-fluoropyridine-6-carboxylate (regioisomer reference); 3-Fluoro-6-bromopicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Bromo-3-Fluoropyridine-2-Carboxylate adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity for research and commercial use. All batches are fully characterized by NMR, HPLC, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.