Description

3-Bromo-6-Hydroxy-2-Pyridinecarboxylic Acid is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate. This compound is particularly significant for its bifunctional reactivity, offering distinct sites for bromination and carboxylation chemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require halogenated pyridine cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials where the pyridine moiety imparts specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science sectors.
• Academic and R&D Laboratories: Used in fundamental research exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	3-Bromo-6-Hydroxy-2-Pyridinecarboxylic Acid
CAS No.	1214332-33-8
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	6-Hydroxy-3-bromopicolinic acid; 3-Bromo-6-hydroxypicolinic acid; 2-Pyridinecarboxylic acid, 3-bromo-6-hydroxy-; 3-Bromo-6-hydroxy-pyridine-2-carboxylic acid; 3-Bromo-6-hydroxypyridine-2-carboxylic acid; 3-Bromopyridine-2,6-diol-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Hydroxy-2-Pyridinecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.