Description

3-Chloro-2-Fluoro-6-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This product is primarily sought by research and development teams in the agrochemical and pharmaceutical industries for the synthesis of novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with improved metabolic stability and bioavailability.
• Material Science Research: Employed in the development of specialty chemicals, liquid crystals, and advanced polymers that require specific halogenated aromatic cores.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Synthesis Reagent: Acts as a fluorinated synthon in organic synthesis for introducing fluorine-containing motifs into target molecules.

Basic Information

Product Name	3-Chloro-2-Fluoro-6-(trifluoromethyl)pyridine
CAS No.	1214331-25-5
Molecular Formula	C6H2ClF4N
Molecular Weight	199.53 g/mol
Synonyms	3-Chloro-2-fluoro-6-(trifluoromethyl)pyridine; 2-Fluoro-3-chloro-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-chloro-2-fluoropyridine; Pyridine, 3-chloro-2-fluoro-6-(trifluoromethyl)-; 3-Chloro-2-fluoro-6-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Fluoro-6-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.