Description

3-Bromo-6-Methoxy-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its unique structure, featuring bromine, methoxy, and trifluoromethyl substituents on a pyridine core, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Ligand and Catalyst Design: Utilized to synthesize novel nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis and other specialized chemical transformations.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and discovery chemistry programs aimed at exploring new chemical space and structure-activity relationships (SAR).

Basic Information

Product Name	3-Bromo-6-Methoxy-2-(Trifluoromethyl)Pyridine
CAS No.	1214330-91-2
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	2-(Trifluoromethyl)-3-bromo-6-methoxypyridine; 3-Bromo-6-methoxy-2-(trifluoromethyl)pyridine; 6-Methoxy-3-bromo-2-trifluoromethylpyridine; 2-Trifluoromethyl-3-bromo-6-methoxypyridine; Pyridine, 3-bromo-6-methoxy-2-(trifluoromethyl)-; 3-Bromo-6-methoxy-2-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Methoxy-2-(Trifluoromethyl)Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical development, and we can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.