Description

5-Chloro-2-(4-Fluorophenyl)Pyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which enables the introduction of both chloro and fluoro substituents into complex target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Employed in the synthesis of organic ligands for metal-organic frameworks (MOFs) and other functional materials.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and tags used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine motifs.

Basic Information

Product Name	5-Chloro-2-(4-Fluorophenyl)Pyridine
CAS No.	1214327-65-7
Molecular Formula	C11H7ClFN
Molecular Weight	207.63 g/mol
Synonyms	2-(4-Fluorophenyl)-5-chloropyridine; 5-Chloro-2-(4-fluorophenyl)pyridine; 4-Fluoro-5-chloro-2-phenylpyridine (ambiguous); (4-Fluorophenyl)-5-chloropyridine; FC-Pyridine Chloro Derivative
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(4-Fluorophenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.