Description

Methyl 3-Bromo-6-Fluoropyridine-2-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its dual reactive sites, the bromine and fluorine substituents, which enable selective cross-coupling and nucleophilic substitution reactions, facilitating the rapid construction of complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the creation of functionalized pyridine derivatives for organic electronic materials, such as OLEDs and conductive polymers.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Facilitates exploratory chemistry in medicinal and synthetic chemistry research programs.

Basic Information

Product Name	Methyl 3-Bromo-6-Fluoropyridine-2-Carboxylate
CAS No.	1214324-98-7
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	Methyl 3-bromo-6-fluoropyridine-2-carboxylate; 3-Bromo-6-fluoro-2-pyridinecarboxylic acid methyl ester; 2-Pyridinecarboxylic acid, 3-bromo-6-fluoro-, methyl ester; Methyl 3-bromo-6-fluoropicolinate; 3-Bromo-6-fluoropicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-6-Fluoropyridine-2-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.