Description

2-Bromo-3-Iodo-5-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and a trifluoromethyl group on the pyridine ring, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, where the halogen atoms and trifluoromethyl group enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: The bromine and iodine substituents provide orthogonal reactivity for sequential Suzuki, Stille, and Sonogashira cross-coupling reactions to build complex heterocyclic systems.
• Ligand and Catalyst Development: Utilized in the preparation of novel nitrogen-based ligands for transition metal catalysis.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	2-Bromo-3-Iodo-5-(Trifluoromethyl)Pyridine
CAS No.	1214323-90-6
Molecular Formula	C6H2BrF3IN
Molecular Weight	361.89 g/mol
Synonyms	2-Bromo-3-iodo-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-bromo-3-iodopyridine; 3-Iodo-2-bromo-5-(trifluoromethyl)pyridine; Pyridine, 2-bromo-3-iodo-5-(trifluoromethyl)-; 2-Bromo-3-iodo-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Iodo-5-(Trifluoromethyl)Pyridine is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.