Description

Methyl 3-Bromo-2-(Trifluoromethyl)Benzoate is a high-purity, multi-functional aromatic ester building block designed for advanced organic synthesis. This compound is valued for its unique trifluoromethyl and bromo substituents, which are critical for modulating the electronic and steric properties of target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions, to form complex biaryl structures.
• Fluorine Chemistry: An essential reagent for introducing the trifluoromethyl group into complex molecular architectures, a common strategy in modern drug design.

Basic Information

Product Name	Methyl 3-Bromo-2-(Trifluoromethyl)Benzoate
CAS No.	1214323-47-3
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	3-Bromo-2-(trifluoromethyl)benzoic acid methyl ester; Methyl 3-bromo-α,α,α-trifluoro-o-toluate; Benzoic acid, 3-bromo-2-(trifluoromethyl)-, methyl ester; 2-(Trifluoromethyl)-3-bromobenzoic acid methyl ester; Methyl 3-bromo-2-trifluoromethylbenzoate; 3-Bromo-2-trifluoromethylbenzoic acid methyl ester; Methyl ester of 3-bromo-2-(trifluoromethyl)benzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-2-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.