Description

3-Bromo-2-Chloropyridine-4-Carboxylic Acid is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated pyridine core provides bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated heterocycles.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry, including cross-coupling and functional group transformation studies.

Basic Information

Product Name	3-Bromo-2-Chloropyridine-4-Carboxylic Acid
CAS No.	1214323-32-6
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	2-Chloro-3-bromopyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-bromo-2-chloro-; 3-Bromo-2-chloroisonicotinic acid; 3-Bromo-2-chloro-4-pyridinecarboxylic acid; 2-Chloro-3-bromoisonicotinic acid; 1214323-32-6; 3-Br-2-Cl-4-PyCOOH
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Chloropyridine-4-Carboxylic Acid is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.