Description

5-Methyl-2-Phenylpyridin-3-Amine is a high-purity, specialized aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized pyridine core, which serves as a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in charge-transport layers.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized aryl-amine groups.
• Dye & Pigment Industry: Acts as an intermediate in the production of specialized dyes and colorants due to its amine and aromatic functionalities.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories worldwide.

Basic Information

Product Name	5-Methyl-2-Phenylpyridin-3-Amine
CAS No.	1214323-20-2
Molecular Formula	C12H12N2
Molecular Weight	184.24 g/mol
Synonyms	3-Amino-5-methyl-2-phenylpyridine; 2-Phenyl-5-methylpyridin-3-amine; 5-Methyl-2-phenyl-3-pyridinamine; 3-Pyridinamine, 5-methyl-2-phenyl-; 1214323-20-2; 5-Methyl-2-phenyl-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Phenylpyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.