Description

2-Fluoro-3-Iodo-4-Methylpyridine is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring strategically placed fluorine and iodine substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the halogenated pyridine core can contribute to biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of advanced organic electronic materials, such as OLEDs or semiconductors.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille), enabling rapid diversification of molecular libraries.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	2-Fluoro-3-Iodo-4-Methylpyridine
CAS No.	1214323-08-6
Molecular Formula	C6H5FIN
Molecular Weight	237.01 g/mol
Synonyms	4-Methyl-2-fluoro-3-iodopyridine; 3-Iodo-2-fluoro-4-methylpyridine; 2-Fluoro-3-iodo-4-picoline; 2-Fluoro-3-iodo-4-methylpyridine; 1214323-08-6; 4-Methyl-3-iodo-2-fluoropyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodo-4-Methylpyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs and ensure our products meet the stringent requirements for use in pharmaceutical and advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.