Description

(2R)-2-Amino-2-(2-Bromo(4-Pyridyl))Ethan-1-Ol is a high-purity chiral building block featuring a brominated pyridine core and an amino alcohol functional group. This compound is critical for the synthesis of complex molecules where stereochemistry and specific halogen placement are essential for biological activity and material properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the construction of advanced herbicide and pesticide intermediates, leveraging the reactivity of the bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological pathways due to its modifiable pyridine and amino alcohol groups.
• Material Science Research: Acts as a building block for functionalized polymers or metal-organic frameworks (MOFs) requiring specific molecular recognition sites.

Basic Information

Product Name	(2R)-2-Amino-2-(2-Bromo(4-Pyridyl))Ethan-1-Ol
CAS No.	1213929-35-1
Molecular Formula	C7H9BrN2O
Molecular Weight	217.07 g/mol
Synonyms	(2R)-2-Amino-2-(2-bromopyridin-4-yl)ethanol; 2-Bromo-4-((R)-2-amino-2-hydroxyethyl)pyridine; 4-Pyridineethanol, 2-amino-2-(2-bromo-4-pyridinyl)-, (2R)-; (R)-2-Amino-2-(2-bromo-4-pyridyl)ethanol; 2-Bromo-4-[(1R)-2-amino-2-hydroxyethyl]pyridine; (R)-2-(2-Bromopyridin-4-yl)-2-aminoethanol; 1213929-35-1; BR-1213929-35-1
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-(2-Bromo(4-Pyridyl))Ethan-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.