Description

Methyl (2R)-2-Amino-2-(3-Chlorophenyl)Acetate is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates. Its defined stereochemistry at the 2-position provides a critical handle for constructing enantiomerically pure active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of advanced, optically active pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the study and development of novel chiral catalysts.
• Peptidomimetics & Bioactive Molecule Construction: Employed in medicinal chemistry for creating constrained peptide analogs and other bioactive compounds.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in regulatory submissions.

Basic Information

Product Name	Methyl (2R)-2-Amino-2-(3-Chlorophenyl)Acetate
CAS No.	1213851-82-1
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	(R)-Methyl 2-Amino-2-(3-chlorophenyl)acetate; (R)-Methyl 2-Amino-(3-chlorophenyl)acetate; Methyl (R)-2-Amino-2-(3-chlorophenyl)acetate; (2R)-2-Amino-2-(3-chlorophenyl)acetic acid methyl ester; D-3-Chlorophenylglycine methyl ester; (R)-3-Chlorophenylglycine methyl ester; (R)-Methyl 3-chlorophenylglycinate
EINECS	Contact for details

Quality Control

Our Methyl (2R)-2-Amino-2-(3-Chlorophenyl)Acetate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.