Description

Methyl (1R)-1-Aminoindane-5-Carboxylate is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing active pharmaceutical ingredients (APIs) and advanced organic molecules. This compound is essential for research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex molecules with defined stereocenters via various coupling and functionalization reactions.
• Agrochemical Research: Used in the development of new chiral active ingredients for crop protection products, leveraging its indane scaffold.
• Ligand and Catalyst Development: Employed as a precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in academic and contract research organizations (CROs).
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	Methyl (1R)-1-Aminoindane-5-Carboxylate
CAS No.	1213609-13-2
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(1R)-1-Amino-2,3-dihydro-1H-indene-5-carboxylic acid methyl ester; Methyl (1R)-1-amino-2,3-dihydro-1H-indene-5-carboxylate; (R)-Methyl 1-aminoindane-5-carboxylate; (R)-1-Aminoindane-5-carboxylic acid methyl ester; (1R)-1-Aminoindane-5-carboxylic acid methyl ester; Aminoindane carboxylate ester; (R)-AIDC methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (1R)-1-Aminoindane-5-Carboxylate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.