Description

(S)-2-Amino-2-(3,5-Difluoropyridin-2-Yl)Ethanol is a high-purity chiral building block and intermediate of significant importance in modern pharmaceutical research and development. Its core value lies in its unique molecular structure, which incorporates a stereogenic center and a difluoropyridine moiety, making it a critical precursor for the synthesis of targeted bioactive molecules. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and advanced fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel small-molecule drugs, especially in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Bioconjugation and Probe Synthesis: Utilized in the design and synthesis of molecular probes and bioconjugates for diagnostic and biochemical research applications.
• Academic and Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and exploratory chemistry projects.
• Process Chemistry & Scale-Up: A critical starting material for optimizing and scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.

Basic Information

Item	Details
Product Name	(S)-2-Amino-2-(3,5-Difluoropyridin-2-Yl)Ethanol
CAS No.	1213486-60-2
Molecular Formula	C7H8F2N2O
Molecular Weight	174.15 g/mol
Synonyms	(S)-2-Amino-2-(3,5-difluoropyridin-2-yl)ethan-1-ol; (S)-2-(3,5-Difluoropyridin-2-yl)-2-aminoethanol; (S)-2-Amino-2-(3,5-difluoro-2-pyridyl)ethanol; (S)-1-(3,5-Difluoropyridin-2-yl)-2-aminoethanol; (S)-2-(3,5-Difluoro-2-pyridinyl)-2-aminoethanol; (S)-2-(3,5-Difluoropyridin-2-yl)glycinol; (S)-Amino(3,5-difluoropyridin-2-yl)methanol
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-2-(3,5-Difluoropyridin-2-Yl)Ethanol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chemical purity, enantiomeric excess, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for critical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.