Description

(2R)-2-Amino-2-(5-Chloro(2-Pyridyl))Ethan-1-Ol CAS NO 1213442-79-5 is a high-purity chiral amino alcohol building block featuring a pyridine core. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of active pharmaceutical ingredients (APIs) and chiral ligands. It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers engaged in developing novel therapeutics, particularly in areas requiring stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, especially those targeting the central nervous system.
• Catalyst & Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Agrochemical Research: Serves as a building block for developing advanced, optically active crop protection agents.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(2R)-2-Amino-2-(5-Chloro(2-Pyridyl))Ethan-1-Ol
CAS No.	1213442-79-5
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	(R)-2-Amino-2-(5-chloropyridin-2-yl)ethanol; (2R)-2-Amino-2-(5-chloro-2-pyridinyl)ethanol; 5-Chloro-2-((R)-2-amino-2-hydroxyethyl)pyridine; (R)-5-Chloro-2-(2-amino-2-hydroxyethyl)pyridine; 2-Pyridineethanol, 2-amino-5-chloro-, (2R)-; (R)-2-Amino-2-(5-chloro-2-pyridyl)ethanol; (R)-Amino-(5-chloro-2-pyridyl)ethanol
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-(5-Chloro(2-Pyridyl))Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.