Description

Methyl 3-((2R)Pyrrolidin-2-Yl)Benzoate CAS NO 1213428-31-9 is a chiral, non-racemic benzoate derivative featuring a pyrrolidine moiety, serving as a high-value synthetic intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemistry in the development of complex molecules, particularly active pharmaceutical ingredients (APIs). Its primary utility lies in the pharmaceutical and agrochemical sectors, where it is employed in the construction of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides.
• Ligand and Catalyst Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme mechanisms and receptor interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Employed in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Methyl 3-((2R)Pyrrolidin-2-Yl)Benzoate
CAS No.	1213428-31-9
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	Methyl 3-[(2R)-2-Pyrrolidinyl]benzoate; (R)-Methyl 3-(2-Pyrrolidinyl)benzoate; Benzoic acid, 3-[(2R)-2-pyrrolidinyl]-, methyl ester; Methyl 3-((R)-pyrrolidin-2-yl)benzoate; 1213428-31-9; (R)-Methyl 3-(pyrrolidin-2-yl)benzoate; Methyl (R)-3-(pyrrolidin-2-yl)benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-((2R)Pyrrolidin-2-Yl)Benzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment, supporting compliance in GMP-oriented applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.