Description

(2S)-2-Amino-2-(5-Fluoro(2-Pyridyl))Ethan-1-Ol is a high-purity chiral amino alcohol building block featuring a fluorinated pyridine moiety. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, particularly in the development of targeted therapies and active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where its specific stereochemistry and functional groups enable precise molecular construction.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutics.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring fluorinated pyridine scaffolds.
• Asymmetric Catalysis: Serves as a precursor or ligand in asymmetric synthesis for creating enantiomerically pure compounds.
• Agrochemical Research: Employed in the development of new generation pesticides and herbicides that utilize fluorinated heterocycles for enhanced activity.
• Fine Chemical Production: A valuable building block for custom synthesis and the manufacture of specialty chemicals with specific optical activity.
• Bioconjugation & Probe Development: Useful in medicinal chemistry for creating molecular probes and bioconjugates due to its amino and hydroxyl functional groups.

Basic Information

Product Name	(2S)-2-Amino-2-(5-Fluoro(2-Pyridyl))Ethan-1-Ol
CAS No.	1213320-37-6
Molecular Formula	C7H9FN2O
Molecular Weight	156.16 g/mol
Synonyms	(S)-2-Amino-2-(5-fluoropyridin-2-yl)ethanol; 2-Pyridineethanol, 2-amino-5-fluoro-, (2S)-; 5-Fluoro-2-((S)-2-amino-2-hydroxyethyl)pyridine; (2S)-2-Amino-2-(5-fluoropyridin-2-yl)ethan-1-ol; (S)-5-Fluoro-2-(2-amino-2-hydroxyethyl)pyridine; 1213320-37-6; (S)-Amino(5-fluoro-2-pyridyl)methanol
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-2-(5-Fluoro(2-Pyridyl))Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.