Description

(4S)-7-Bromo-3,4-Dihydro-2H-1-Benzopyran-4-Amine is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its defined stereochemistry and functional groups, which make it a critical precursor in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used as a building block in the production of advanced herbicides, fungicides, and insecticides, leveraging its brominated chromane structure.
• Organic Synthesis & Catalysis: Serves as a versatile starting material or ligand precursor in asymmetric synthesis and catalytic reactions due to its amine functionality and stereogenic center.
• Life Science Research: Employed in biochemical and pharmacological studies as a reference standard or probe molecule to investigate biological pathways and receptor interactions.
• Material Science: Potential precursor for specialty polymers or advanced organic materials requiring specific optical or electronic properties.

Basic Information

Product Name	(4S)-7-Bromo-3,4-Dihydro-2H-1-Benzopyran-4-Amine
CAS No.	1213134-75-8
Molecular Formula	C9H10BrNO
Molecular Weight	228.09 g/mol
Synonyms	(4S)-7-Bromo-3,4-dihydro-2H-chromen-4-amine; (4S)-7-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine; 7-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine, (4S)-; (S)-7-Bromo-3,4-dihydro-2H-chromen-4-amine; 4-Amino-7-bromo-2H-chromane, (S)-; 1213134-75-8; (S)-7-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine
EINECS	Contact for details

Quality Control

Our (4S)-7-Bromo-3,4-Dihydro-2H-1-Benzopyran-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting compliance with cGMP and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.