Description

(S)-3-(Pyridin-4-Yl)Morpholine is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its defined stereochemistry and unique heterocyclic structure, which is crucial for imparting specific biological activity in drug discovery and development. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for kinase inhibitors and receptor modulators.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and medicinal chemistry applications.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and protein function.
• Agrochemical Research: Potential intermediate in the development of advanced crop protection agents with specific modes of action.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for method development and exploratory synthesis projects.

Basic Information

Product Name	(S)-3-(Pyridin-4-Yl)Morpholine
CAS No.	1213126-61-4
Molecular Formula	C9H12N2O
Molecular Weight	164.21 g/mol
Synonyms	(S)-3-(4-Pyridinyl)morpholine; (S)-3-(Pyridin-4-yl)morpholine; (S)-3-(4-Pyridyl)morpholine; (S)-4-(Morpholin-3-yl)pyridine; (S)-3-Pyridin-4-ylmorpholine; (3S)-3-(Pyridin-4-yl)morpholine; (S)-3-(4-Pyridyl)-1,4-oxazinane; (S)-3-(4-Pyridinyl)-1,4-oxazinane
EINECS	Contact for details

Quality Control

Our (S)-3-(Pyridin-4-Yl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from HPLC, chiral analysis, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.