Description

Methyl (3R)-3-Amino-3-(2-Methoxyphenyl)Propanoate CAS NO 1213105-49-7 is a high-purity chiral amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for constructing complex molecules with high biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Peptidomimetics Research: Serves as a constrained amino acid analog for the design and synthesis of novel peptide-like molecules with enhanced metabolic stability.
• Agrochemical Development: Employed in the research phase for creating new chiral active ingredients for crop protection products.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Detail
Product Name	Methyl (3R)-3-Amino-3-(2-Methoxyphenyl)Propanoate
CAS No.	1213105-49-7
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(R)-Methyl 3-Amino-3-(2-methoxyphenyl)propanoate; Methyl (R)-3-Amino-3-(o-methoxyphenyl)propionate; (3R)-3-Amino-3-(2-methoxyphenyl)propanoic Acid Methyl Ester; (R)-3-Amino-3-(2-methoxyphenyl)propionic Acid Methyl Ester; 1213105-49-7; (R)-3-Amino-3-(o-methoxyphenyl)propanoate Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl (3R)-3-Amino-3-(2-Methoxyphenyl)Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. All products undergo rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.