Description

(1R)-1-[5-(Trifluoromethyl)(2-Pyridyl)]Ethylamine CAS NO 1213052-96-0 is a high-purity chiral amine building block featuring a trifluoromethylpyridine moiety, prized for its ability to impart metabolic stability and modulate lipophilicity in molecular design. This compound is essential for research and development chemists requiring a specific enantiomer to achieve desired biological activity and pharmacokinetic profiles. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Key chiral intermediate in the synthesis of novel pharmaceutical candidates, particularly in central nervous system (CNS) and oncology research.
• Building block for agrochemical active ingredients, leveraging the trifluoromethyl group for enhanced efficacy and environmental stability.
• Precursor in the development of ligands and catalysts for asymmetric synthesis.
• Research chemical for medicinal chemistry and structure-activity relationship (SAR) studies.
• Starting material for the synthesis of advanced fine chemicals and specialty materials.

Basic Information

Product Name	(1R)-1-[5-(Trifluoromethyl)(2-Pyridyl)]Ethylamine
CAS No.	1213052-96-0
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	(R)-1-[5-(Trifluoromethyl)pyridin-2-yl]ethan-1-amine; (1R)-1-[5-(Trifluoromethyl)-2-pyridinyl]ethylamine; (R)-1-(5-(Trifluoromethyl)pyridin-2-yl)ethanamine; (R)-α-Methyl-5-(trifluoromethyl)-2-pyridinemethanamine; (R)-2-(1-Aminoethyl)-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our (1R)-1-[5-(Trifluoromethyl)(2-Pyridyl)]Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and development standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.