Description

(S)-2-(2,5-Dichlorophenyl)Piperidine is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical and agrochemical research. Its value lies in its defined stereochemistry and functionalized aromatic-piperidine scaffold, enabling the synthesis of targeted bioactive molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel central nervous system (CNS) active drugs, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in constructing advanced intermediates for crop protection agents, including herbicides and insecticides with specific stereochemical requirements.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and as a molecular scaffold for probing biological pathways and protein interactions.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Item	Details
Product Name	(S)-2-(2,5-Dichlorophenyl)Piperidine
CAS No.	1213008-28-6
Molecular Formula	C11H13Cl2N
Molecular Weight	230.13 g/mol
Synonyms	(S)-2-(2,5-Dichlorophenyl)piperidine; (2S)-2-(2,5-Dichlorophenyl)piperidine; (S)-2,5-Dichloro-α-piperidinobenzyl; (S)-2-(2,5-Dichlorophenyl)piperidine hydrochloride (salt forms); 1213008-28-6; (S)-2-(2,5-Dichlorophenyl)azepane (related); (S)-2-(2,5-Dichlorophenyl)hexahydropyridine
EINECS	Contact for details

Quality Control

Our (S)-2-(2,5-Dichlorophenyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.