Description

(S)-3-(Piperidin-2-Yl)Benzoic Acid CAS NO 1212875-03-0 is a high-purity chiral building block featuring a benzoic acid moiety linked to a piperidine ring. This compound is of significant value in pharmaceutical research and development as a key intermediate for constructing complex molecules with specific stereochemistry. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease therapeutic areas.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce specific pharmacophores and modulate the physicochemical properties of drug-like molecules.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scalable synthesis of Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology: Can be utilized as a molecular probe or a linker component in the development of chemical tools for studying biological pathways.
• Asymmetric Synthesis: Employed as a chiral auxiliary or a building block in enantioselective synthesis to create stereochemically defined compounds.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	(S)-3-(Piperidin-2-Yl)Benzoic Acid
CAS No.	1212875-03-0
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	(S)-3-(2-Piperidyl)benzoic acid; (S)-3-(Piperidin-2-yl)benzoic acid; Benzoic acid, 3-(2-piperidinyl)-, (S)-; (S)-3-Piperidin-2-yl-benzoic acid; (S)-3-(2-Piperidinyl)benzoic acid; (2S)-3-(2-Piperidyl)benzoic acid; (S)-3-(Piperidin-2-yl)benzoic acid CAS 1212875-03-0
EINECS	Contact for details

Quality Control

Our (S)-3-(Piperidin-2-Yl)Benzoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data including HPLC purity, chiral purity, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.