Description

(R)-1-(2-Chloropyridin-4-Yl)Ethan-1-Amine CAS NO 1212846-40-6 is a high-purity chiral amine building block featuring a chloropyridine moiety. This compound is critical for the synthesis of complex, biologically active molecules where stereochemistry is a key determinant of efficacy. It is primarily sought after by pharmaceutical and agrochemical R&D organizations for the development of new active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used in the creation of advanced chiral herbicides, fungicides, and insecticides, where the (R)-enantiomer provides specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a molecular probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(R)-1-(2-Chloropyridin-4-Yl)Ethan-1-Amine
CAS No.	1212846-40-6
Molecular Formula	C7H9ClN2
Molecular Weight	156.61 g/mol
Synonyms	(R)-1-(2-Chloro-4-pyridinyl)ethanamine; (R)-1-(2-Chloropyridin-4-yl)ethanamine; (R)-α-Methyl-2-chloro-4-pyridinemethanamine; (R)-2-Chloro-4-(1-aminoethyl)pyridine; (R)-4-(1-Aminoethyl)-2-chloropyridine; (R)-Enantiomer of 1-(2-Chloropyridin-4-yl)ethan-1-amine; (R)-CPEA
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Chloropyridin-4-Yl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.