Description

n-(4-Fluorophenyl)-2'-(2-Methoxyethyl)-1'-Oxo-1',4'-Dihydro-2'H-Spiro[Cyclopentane-1,3'-Isoquinoline]-4'-Carboxamide CAS NO 1212476-27-1 is a high-purity, synthetic organic compound featuring a complex spirocyclic and isoquinoline-based molecular architecture. This compound is of significant value as a key advanced intermediate or building block in modern pharmaceutical research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, or inflammatory diseases.
• Medicinal Chemistry Research: Used by R&D scientists for structure-activity relationship (SAR) studies, library synthesis, and lead optimization programs due to its unique spirocyclic scaffold.
• Biochemical Tool Compound: Potential application as a research-grade ligand or inhibitor in biochemical assays to study specific enzyme or receptor interactions.
• Process Chemistry Development: Employed in scaling up synthetic routes from milligram to kilogram scale for preclinical and clinical trial material production.
• Custom Synthesis & Contract Manufacturing: Supplied to partners requiring custom chemical synthesis services for proprietary drug discovery projects.
• Academic Research: Utilized in university laboratories for advanced organic synthesis methodology development and heterocyclic chemistry studies.

Basic Information

Item	Details
Product Name	n-(4-Fluorophenyl)-2'-(2-Methoxyethyl)-1'-Oxo-1',4'-Dihydro-2'H-Spiro[Cyclopentane-1,3'-Isoquinoline]-4'-Carboxamide
CAS No.	1212476-27-1
Molecular Formula	C23H23FN2O3
Molecular Weight	394.44 g/mol
Synonyms	4'-Carboxamide, n-(4-Fluorophenyl)-2'-(2-Methoxyethyl)-1'-Oxo-1',4'-Dihydro-2'H-Spiro[Cyclopentane-1,3'-Isoquinoline]; 1212476-27-1; Spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxamide, N-(4-fluorophenyl)-1',4'-dihydro-2'-(2-methoxyethyl)-1'-oxo-; N-(4-Fluorophenyl)-2'-(2-methoxyethyl)-1'-oxo-1',4'-dihydro-2'H-spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxamide; Spirocyclic Isoquinoline Carboxamide Derivative
EINECS	Contact for details

Quality Control

Our production of n-(4-Fluorophenyl)-2'-(2-Methoxyethyl)-1'-Oxo-1',4'-Dihydro-2'H-Spiro[Cyclopentane-1,3'-Isoquinoline]-4'-Carboxamide adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and meet the exacting standards of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.