Description

(2S)-2-(1,3-Dioxo-1,3-Dihydro-2H-Pyrrolo[3,4-C]-Pyridin-2-Yl)Propanoic Acid is a high-purity, chiral organic compound featuring a fused pyrrolopyridine-dione scaffold. This molecule matters as a sophisticated pharmaceutical intermediate and key building block for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Active Pharmaceutical Ingredient (API) Development: Used as a core structural component in the research and scale-up of new APIs.
• Bioconjugation & Prodrug Synthesis: The carboxylic acid functionality enables its use in creating prodrugs or conjugating with biomolecules for targeted drug delivery systems.
• Chemical Biology Research: Employed as a tool compound or a specialty reagent in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective synthesis due to its defined (2S) configuration.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S)-2-(1,3-Dioxo-1,3-Dihydro-2H-Pyrrolo[3,4-C]-Pyridin-2-Yl)Propanoic Acid
CAS No.	1212191-11-1
Molecular Formula	C11H8N2O4
Molecular Weight	232.19 g/mol
Synonyms	(S)-2-(1,3-Dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)propanoic acid; 2H-Pyrrolo[3,4-c]pyridine-2-propanoic acid, 1,3-dihydro-1,3-dioxo-, (2S)-; L-2-(1,3-Dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)propanoic acid; (S)-2-(1,3-Dioxoisoindolin-2-yl)propanoic acid fused pyridine analog; (2S)-2-(1,3-Dioxo-2H-pyrrolo[3,4-c]pyridin-2(1H,3H)-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our (2S)-2-(1,3-Dioxo-1,3-Dihydro-2H-Pyrrolo[3,4-C]-Pyridin-2-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be kept in its original packaging until use to minimize exposure. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.