Description

(1R*,2S*,5R*)-2-Benzyloxycarbonylamino-5-(Toluene-4-Sulfonyloxy)-Cyclohexanecarboxylic Acid Ethyl Ester is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters as a key protected intermediate, enabling the precise construction of complex molecules with defined stereocenters. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly those containing functionalized cyclohexane scaffolds.
• Chiral Building Block: Used in asymmetric synthesis to introduce specific stereochemistry into target molecules, leveraging its defined (1R*,2S*,5R*) configuration.
• Peptidomimetic Research: Serves as a constrained, non-natural amino acid derivative for the development of novel peptide-like compounds with enhanced metabolic stability.
• Agrochemical Synthesis: Employed in the research and development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including novel protection/deprotection strategies and C-O bond formation.
• Custom Synthesis Starting Material: Provides a versatile platform for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	(1R*,2S*,5R*)-2-Benzyloxycarbonylamino-5-(Toluene-4-Sulfonyloxy)-Cyclohexanecarboxylic Acid Ethyl Ester
CAS No.	1212170-46-1
Molecular Formula	C24H29NO7S
Molecular Weight	475.56 g/mol
Synonyms	Ethyl (1R*,2S*,5R*)-2-[[(benzyloxy)carbonyl]amino]-5-[(4-methylphenyl)sulfonyl]oxy]cyclohexanecarboxylate; (1R*,2S*,5R*)-2-(N-Cbz-amino)-5-tosyloxy-cyclohexanecarboxylic acid ethyl ester; N-Cbz-2-amino-5-tosyloxy-cyclohexanecarboxylic acid ethyl ester (relative stereochemistry); Z-2-Amino-5-tosyloxy-cyclohexanecarboxylic acid ethyl ester; 2-[(Benzyloxycarbonyl)amino]-5-[(4-methylbenzenesulfonyl)oxy]cyclohexanecarboxylic acid ethyl ester; Ethyl 2-[(benzyloxycarbonyl)amino]-5-[(4-methylphenyl)sulfonyloxy]cyclohexanecarboxylate; 1212170-46-1; C24H29NO7S
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (for specified stereoisomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.