Description

2-(Methylthio)-α-Oxo-4-Pyrimidineacetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidine backbone. This compound is valued for its role as a key synthetic building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting antiviral or anticancer pathways.
• Agrochemical Research: Used in the development and production of advanced pesticides and herbicides due to its bioactive pyrimidine structure.
• Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in organic and medicinal chemistry.
• Academic & R&D: Employed in laboratory-scale research for method development and studying structure-activity relationships (SAR).

Basic Information

Product Name	2-(Methylthio)-α-Oxo-4-Pyrimidineacetic Acid Ethyl Ester
CAS No.	1211595-04-8
Molecular Formula	C10H12N2O3S
Molecular Weight	240.28 g/mol
Synonyms	Ethyl 2-(methylthio)-α-oxo-4-pyrimidineacetate; 4-Pyrimidineacetic acid, 2-(methylthio)-α-oxo-, ethyl ester; Ethyl 2-(methylsulfanyl)-2-oxo-2H-pyrimidine-4-carboxylate; 2-(Methylthio)-2-oxo-2H-pyrimidine-4-carboxylic acid ethyl ester; 1211595-04-8; Ethyl (2-methylsulfanyl-2-oxo-2H-pyrimidin-4-yl)acetate
EINECS	Contact for details

Quality Control

Our production of 2-(Methylthio)-α-Oxo-4-Pyrimidineacetic Acid Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.