Description

2-Methyl-6-(Trifluoromethyl)Isonicotinic Acid is a high-value, multi-functional heterocyclic building block characterized by its pyridine core, methyl substituent, and trifluoromethyl group. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where it imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas targeting central nervous system (CNS) disorders and inflammatory diseases.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and organic electronic materials due to its unique electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Methyl-6-(Trifluoromethyl)Isonicotinic Acid
CAS No.	1211590-99-6
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	6-(Trifluoromethyl)-2-picolinic acid; 2-Methyl-6-(trifluoromethyl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-methyl-6-(trifluoromethyl)-; 2-Methyl-6-trifluoromethylisonicotinic acid; 6-Trifluoromethyl-2-picolinic acid; 2-Methyl-6-(trifluoromethyl)nicotinic acid (isomer); 2-Methyl-6-(trifluoromethyl)isonicotinate (acid form)
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-6-(Trifluoromethyl)Isonicotinic Acid is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.