Description

4-Amino-5-Fluoro-2-Methylpyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both amino and fluoro substituents on a methylated pyridine core, makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its fluorine-containing pyridine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological systems and enzyme activity.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Amino-5-Fluoro-2-Methylpyridine
CAS No.	1211590-22-5
Molecular Formula	C6H7FN2
Molecular Weight	126.13 g/mol
Synonyms	5-Fluoro-2-methylpyridin-4-amine; 2-Methyl-5-fluoropyridin-4-amine; 4-Amino-5-fluoro-2-picoline; 5-Fluoro-4-amino-2-methylpyridine; 4-Amino-5-fluoro-2-methylpyridine; 2-Methyl-4-amino-5-fluoropyridine; 5-Fluoro-2-methyl-4-pyridinamine
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Fluoro-2-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.