Description

5-Cyclopropylnicotinaldehyde is a high-purity, versatile heterocyclic aldehyde building block essential for advanced organic synthesis. This compound is particularly valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the cyclopropyl and pyridine moieties confer unique biological and physicochemical properties. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates targeting various therapeutic areas, including central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the nicotinaldehyde scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional organic materials, such as organic semiconductors and liquid crystals.
• Chemical Biology Probes: Utilized to develop molecular probes and fluorescent tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis services catering to specific client R&D projects.

Basic Information

Product Name	5-Cyclopropylnicotinaldehyde
CAS No.	1211589-30-8
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	5-Cyclopropyl-3-pyridinecarboxaldehyde; 5-Cyclopropylpyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 5-cyclopropyl-; Nicotinaldehyde, 5-cyclopropyl-; Cyclopropylnicotinaldehyde
EINECS	Contact for details

Quality Control

Our 5-Cyclopropylnicotinaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to quality supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.