Description

1H-Pyrazolo[3,4-B]Pyridine-3-Methanol CAS NO 1211589-17-1 is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and anti-inflammatory research.
• Kinase Inhibitor Development: Core scaffold for the design and synthesis of small molecule kinase inhibitors due to its pyrazolopyridine structure.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to improve drug potency and selectivity.
• Biochemical Probe Synthesis: Serves as a precursor for creating chemical probes to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-3-Methanol
CAS No.	1211589-17-1
Molecular Formula	C7H7N3O
Molecular Weight	149.15 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridin-3-ylmethanol; 3-(Hydroxymethyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-3-methanol; Pyrazolo[3,4-b]pyridine-3-methanol; 3-Pyrazolo[3,4-b]pyridinemethanol
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-3-Methanol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.