Description

5-Bromo-2-Methoxypyridin-3-Ol is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules.

Basic Information

Product Name	5-Bromo-2-Methoxypyridin-3-Ol
CAS No.	1211589-04-6
Molecular Formula	C6H6BrNO2
Molecular Weight	204.02 g/mol
Synonyms	3-Hydroxy-5-bromo-2-methoxypyridine; 5-Bromo-2-methoxy-3-pyridinol; 5-Bromo-3-hydroxy-2-methoxypyridine; 2-Methoxy-5-bromopyridin-3-ol; 3-Pyridinol, 5-bromo-2-methoxy-; 1211589-04-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxypyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.