Description

2-Chloro-3-Methoxy-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique molecular structure, featuring chloro, methoxy, and trifluoromethyl substituents, provides exceptional reactivity and stability for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for creating specialized ligands, catalysts, and functionalized polymers with tailored electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex pyridine motifs into target molecules.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	2-Chloro-3-Methoxy-4-(Trifluoromethyl)Pyridine
CAS No.	1211588-85-0
Molecular Formula	C8H5ClF3NO
Molecular Weight	223.58 g/mol
Synonyms	2-Chloro-3-methoxy-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-chloro-3-methoxypyridine; 3-Methoxy-2-chloro-4-trifluoromethylpyridine; 2-Chloro-3-methoxy-4-trifluoromethylpyridine; Pyridine, 2-chloro-3-methoxy-4-(trifluoromethyl)-; CAS 1211588-85-0
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methoxy-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.