Description

5-Bromo-2-Fluoro-4-Methoxypyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for introducing specific functional groups into complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and methoxy groups for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine motifs.
• Academic & R&D: Employed in university and institutional laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-2-Fluoro-4-Methoxypyridine
CAS No.	1211588-65-6
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	2-Fluoro-5-bromo-4-methoxypyridine; 4-Methoxy-5-bromo-2-fluoropyridine; 5-Bromo-2-fluoro-4-methoxypyridine; 2-Fluoro-4-methoxy-5-bromopyridine; Pyridine, 5-bromo-2-fluoro-4-methoxy-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-4-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.