Description

2-(1,1-Difluoroethyl)Pyridin-4-Amine is a specialized pyridine derivative featuring a difluoroethyl substituent, making it a valuable fluorinated building block in advanced organic synthesis. This compound is particularly significant for its role in medicinal chemistry, where its unique structure is leveraged to modulate the pharmacokinetic and physicochemical properties of drug candidates. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the creation of novel, high-value molecules.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides and pesticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, or advanced polymers with tailored properties.
• Chemical Biology Probes: Employed in the creation of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(1,1-Difluoroethyl)Pyridin-4-Amine
CAS No.	1211586-93-4
Molecular Formula	C7H8F2N2
Molecular Weight	158.15 g/mol
Synonyms	4-Amino-2-(1,1-difluoroethyl)pyridine; 2-(1,1-Difluoroethyl)-4-pyridinamine; 4-Pyridinamine, 2-(1,1-difluoroethyl)-; 2-(Difluoroethyl)pyridin-4-amine; 2-(1,1-Difluoroethyl)-4-aminopyridine; 4-Amino-2-(α,α-difluoroethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(1,1-Difluoroethyl)Pyridin-4-Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.